gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2502 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY TACHYKININ RECEPTOR
SUBFAMILY NK1

Cross References:
UniProt P25103 EMBL S62045 | M74290 | M81797 | M76675 | X65177 | X65178 | X65179 | X65180 | X65181 | M84425 | M84426 | AY462098 | BC074911 | BC074912
InterPro IPR000276 | IPR001681 | IPR000046 GPCRDB nk1r_human
GENEID 6869 MIM 162323
PRINTS PR00237 | PR01024 | PR00244 PFAM PF00001

Details:
NAME TACHYKININ RECEPTOR_NK1_Homo sapiens
DESCRIPTION Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykininreceptor 1).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE TACR1 | NK1R | TAC1R
SEQUENCE 
MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH
KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI
YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC
MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV
SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY
NPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTIST
VVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS
 FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:8999927
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gq/11 REFERENCES:1370820
3GPR0002Galpha-q-Homo sapiens-2
4GPR0029Galpha-11-Homo sapiens
5GPR0237Galpha-q-Homo sapiens-1
Family:Gs REFERENCES:1370820
6GPR0119Galpha-s-Homo sapiens-2
7GPR0263Galpha-s-Homo sapiens-4
8GPR0266Galpha-s-Homo sapiens-5
9GPR0267Galpha-s-Homo sapiens-6
10GPR0277Galpha-s-Homo sapiens-7
11GPR0278Galpha-s-Homo sapiens
12GPR0395Galpha-s-Homo sapiens-3

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
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Laboratory