gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2432 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROSTANOID RECEPTOR
SUBFAMILY EP3

Cross References:
UniProt P43115 | O00326 | Q12943 | Q12944 | Q12945 | Q16546 EMBL S69200 | L27488 | L27489 | L27490 | X83857 | X83858 | X83859 | X83860 | X83861 | X83862 | X83863 | L26976 | S69326 | L32660 | L32661 | L32662 | D38297 | D38298 | D38299 | D38300 | D38301 | U13214 | U13215 | U13216 | U13217 | U13218 | D86096 | D86098 | AY429108 | AL031429 | AL031429 | AL031429 | AL158087 | AL158087 | AL031429 | AL031429 | BC024229
InterPro IPR001481 | IPR000276 | IPR008365 | IPR001244 | IPR000265 GPCRDB pe2r3_human
GENEID 5733 MIM 176806
PRINTS PR00237 | PR00428 | PR01788 | PR00584 | PR00582 PFAM PF00001

Details:
NAME PROSTANOID RECEPTOR_EP3_Homo sapiens
DESCRIPTION Prostaglandin E2 receptor EP3 subtype (Prostanoid EP3 receptor) (PGEreceptor, EP3 subtype) (PGE2-R).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE PTGER3
SEQUENCE 
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
RYHTNNYASSSTSLPCQCSSTLMWSDHLER
 FRAGMENT NO

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Scaffold:
TYPE Muskelin REFERENCES 11006128

Coupling with G-proteins:
Family:Gi/o REFERENCES:11095474
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1
Family:Gq/11 REFERENCES:11095474
8GPR0002Galpha-q-Homo sapiens-2
9GPR0029Galpha-11-Homo sapiens
10GPR0237Galpha-q-Homo sapiens-1
Family:Gs REFERENCES:11095474
11GPR0119Galpha-s-Homo sapiens-2
12GPR0263Galpha-s-Homo sapiens-4
13GPR0266Galpha-s-Homo sapiens-5
14GPR0267Galpha-s-Homo sapiens-6
15GPR0277Galpha-s-Homo sapiens-7
16GPR0278Galpha-s-Homo sapiens
17GPR0395Galpha-s-Homo sapiens-3

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory