gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0007 ::
FAMILY Cyclases
SUBFAMILY Adenylate cyclases
TYPE Adenylate cyclase 2

Cross References:
UniProt Q08462 | Q2NKL8 | Q9UPU2 EMBL AF410885 | BC111743 | AB028983 | X74210 | L21993
InterPro IPR001054 | IPR009398
GENEID 108 MIM 103071
PFAM PF06327 | PF00211

Details:
NAME Adenylate cyclase-2-Homo sapiens-2
DESCRIPTION Adenylate cyclase type 2 (EC 4.6.1.1) (Adenylate cyclase type II) (ATPpyrophosphate-lyase 2) (Adenylyl cyclase 2).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE ADCY2 | KIAA1060
SEQUENCE 
MWQEAMRRRRYLRDRSEEAAGGGDGLPRSRDWLYESYYCMSQQHPLIVFLLLIVMGSCLA
LLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIWICLVAM
GYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSAT
PGGKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQ
ERLLLSLLPAHIAME
 FRAGMENT NO
FUNCTION This is a membrane-bound, calmodulin-insensitives adenylyl cyclase
Interacting with G-proteins:
Family:Gs REFERENCES:15251227 | 15922020 | 14993377 | 11376933
1GPR0119Galpha-s-Homo sapiens-2
2GPR0263Galpha-s-Homo sapiens-4
3GPR0266Galpha-s-Homo sapiens-5
4GPR0267Galpha-s-Homo sapiens-6
5GPR0277Galpha-s-Homo sapiens-7
6GPR0278Galpha-s-Homo sapiens
7GPR0395Galpha-s-Homo sapiens-3
Family:Gbeta REFERENCES:15251227 | 15922020 | 14993377 | 11376933
8GPR0147Gbeta-1-Homo sapiens
9GPR0155Gbeta-2-Homo sapiens
10GPR0160Gbeta-3-Homo sapiens-1
11GPR0164Gbeta-4-Homo sapiens
12GPR0167Gbeta-5-Homo sapiens-2
13GPR0363Gbeta-3-Homo sapiens-2
14GPR0366Gbeta-5-Homo sapiens-1
15GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227 | 15922020 | 14993377 | 11376933
16GPR0176Ggamma-t1-Homo sapiens
17GPR0179Ggamma-2-Homo sapiens
18GPR0183Ggamma-3-Homo sapiens
19GPR0185Ggamma-4-Homo sapiens
20GPR0188Ggamma-5-Homo sapiens-2
21GPR0192Ggamma-7-Homo sapiens
22GPR0195Ggamma-8-Homo sapiens-2
23GPR0198Ggamma-10-Homo sapiens-2
24GPR0199Ggamma-11-Homo sapiens
25GPR0203Ggamma-12-Homo sapiens
26GPR0205Ggamma-13-Homo sapiens
27GPR0210Ggamma-8-Homo sapiens-1
28GPR0253Ggamma-5-Homo sapiens-1
29GPR0364Ggamma-10-Homo sapiens-1

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory