gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0426 ::
FAMILY Ion channels
SUBFAMILY Inwar rectifier K channels
TYPE Kir 3 4(GIRK4)

Cross References:
UniProt P48544 | Q6DK13 | Q6DK14 | Q92807 EMBL U39195 | L47208 | X83582 | U52154 | D50134 | BC069571 | BC074838 | BC069386 | BC069482 | BC069499 | BC074839
InterPro IPR001838 | IPR003277 | IPR013521 | IPR013518
PRODOM PD001103 MIM 600734
PRINTS PR01330 | PR01320 PFAM PF01007

Details:
NAME Kir 3.4(GIRK4)-Homo sapiens-2
DESCRIPTION G protein-activated inward rectifier potassium channel 4 (GIRK4)(Potassium channel, inwardly rectifying subfamily J member 5) (Inwardrectifier K(+) channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiacinward rectifier) (CIR).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE KCNJ5 | GIRK4
SEQUENCE 
MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKC
NVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDH
VGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNA
FMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIK
SRQTKEGEFIPLNQT
 FRAGMENT NO
FUNCTION This potassium channel is controlled by G proteins
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 14963032 | 11779482
1GPR0109Galpha-i3-Homo sapiens
2GPR0218Galpha-i1-Homo sapiens-1
3GPR0226Galpha-i2-Homo sapiens-2
4GPR0261Galpha-i1-Homo sapiens-2
5GPR0365Galpha-i2-Homo sapiens-1
Family:Gq/11 REFERENCES:12661754
6GPR0002Galpha-q-Homo sapiens-2
7GPR0237Galpha-q-Homo sapiens-1
Family:Gbeta REFERENCES:15251227 | 10944236 | 12661754
8GPR0147Gbeta-1-Homo sapiens
9GPR0155Gbeta-2-Homo sapiens
10GPR0160Gbeta-3-Homo sapiens-1
11GPR0164Gbeta-4-Homo sapiens
12GPR0167Gbeta-5-Homo sapiens-2
13GPR0363Gbeta-3-Homo sapiens-2
14GPR0366Gbeta-5-Homo sapiens-1
15GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227 | 10944236
16GPR0176Ggamma-t1-Homo sapiens
17GPR0179Ggamma-2-Homo sapiens
18GPR0183Ggamma-3-Homo sapiens
19GPR0185Ggamma-4-Homo sapiens
20GPR0188Ggamma-5-Homo sapiens-2
21GPR0192Ggamma-7-Homo sapiens
22GPR0195Ggamma-8-Homo sapiens-2
23GPR0198Ggamma-10-Homo sapiens-2
24GPR0199Ggamma-11-Homo sapiens
25GPR0203Ggamma-12-Homo sapiens
26GPR0205Ggamma-13-Homo sapiens
27GPR0210Ggamma-8-Homo sapiens-1
28GPR0253Ggamma-5-Homo sapiens-1
29GPR0364Ggamma-10-Homo sapiens-1

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athina University of Athens
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