gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0413 ::
FAMILY Ion channels
SUBFAMILY Inwar rectifier K channels
TYPE Kir 3 2(GIRK2)

Cross References:
UniProt P48542 | O70290 | P70216 | P70306 | P70307 | P70308 | P70309 | P70454 EMBL U37253 | U11859 | U51122 | U51123 | U51124 | U51125 | U51126 | AF040049 | AF040047 | AF040050 | AF040049 | AF040051 | AF040047 | AF040049 | AF040052 | AF040047 | AF040049 | AF040051 | D86040 | AB029502
InterPro IPR001838 | IPR003275 | IPR013521 | IPR013518 PDB 2E4F
PRODOM PD001103
PRINTS PR01328 | PR01320 PFAM PF01007

Details:
NAME Kir 3.2(GIRK2)-Mus musculus-2
DESCRIPTION G protein-activated inward rectifier potassium channel 2 (GIRK2)(Potassium channel, inwardly rectifying subfamily J member 6) (Inwardrectifier K(+) channel Kir3.2).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Kcnj6 | Girk2 | Kcnj7 | W
SEQUENCE 
MTMAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVR
KDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIR
GDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLG
SIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIR
AKLIKSKQTSEGEFI
 FRAGMENT NO
FUNCTION This potassium channel is controlled by G proteins
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 14963032 | 11779482
1GPR0227Galpha-i2-Mus musculus-2
2GPR0289Galpha-i1-Mus musculus
3GPR0331Galpha-i2-Mus musculus-1
4GPR0385Galpha-i3-Mus musculus
Family:Gq/11 REFERENCES:12661754
5GPR0240Galpha-q-Mus musculus
Family:Gbeta REFERENCES:15251227 | 10944236 | 12661754
6GPR0148Gbeta-1-Mus musculus
7GPR0156Gbeta-2-Mus musculus
8GPR0161Gbeta-3-Mus musculus
9GPR0165Gbeta-4-Mus musculus
10GPR0168Gbeta-5-Mus musculus-2
11GPR0291unclassified_Gbeta-Mus musculus-1
12GPR0318unclassified_Gbeta-Mus musculus-2
13GPR0376Gbeta-5-Mus musculus-3
14GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:15251227 | 10944236 | 12661754
15GPR0178Ggamma-t1-Mus musculus
16GPR0181Ggamma-2-Mus musculus
17GPR0184Ggamma-3-Mus musculus
18GPR0186Ggamma-4-Mus musculus
19GPR0189Ggamma-5-Mus musculus
20GPR0193Ggamma-7-Mus musculus
21GPR0196Ggamma-8-Mus musculus-2
22GPR0200Ggamma-11-Mus musculus
23GPR0204Ggamma-12-Mus musculus
24GPR0206Ggamma-13-Mus musculus
25GPR0211Ggamma-8-Mus musculus-1
26GPR0349Ggamma-1-Mus musculus
27GPR0379Ggamma-10-Mus musculus

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athina University of Athens
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