gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0003 ::
FAMILY Cyclases
SUBFAMILY Adenylate cyclases
TYPE Adenylate cyclase 1

Cross References:
UniProt Q08828 | Q75MI1 EMBL AC069008 | AC091439 | L05500
InterPro IPR001054
GENEID 107 MIM 103072
PFAM PF00211

Details:
NAME Adenylate cyclase-1-Homo sapiens-2
DESCRIPTION Adenylate cyclase type 1 (EC 4.6.1.1) (Adenylate cyclase type I) (ATPpyrophosphate-lyase 1) (Adenylyl cyclase 1) (Ca(2+)/calmodulin-activated adenylyl cyclase).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE ADCY1
SEQUENCE 
MAGAPRGGGGGGGGAGEPGGAERAAGTSRRRGLRACDEEFACPELEALFRGYTLRLEQAA
TLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQ
QVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQLLLVTFVSYALLPVR
SLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQR
KAFLQARSCIEDRLR
 FRAGMENT NO
FUNCTION This is a calmodulin-sensitive adenylyl cyclase
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 15922020 | 14993377 | 11376933
1GPR0109Galpha-i3-Homo sapiens
2GPR0218Galpha-i1-Homo sapiens-1
3GPR0226Galpha-i2-Homo sapiens-2
4GPR0261Galpha-i1-Homo sapiens-2
5GPR0365Galpha-i2-Homo sapiens-1
6GPR0020Galpha-o1-Homo sapiens
7GPR0334Galpha-o-Homo sapiens
Family:Gs REFERENCES:15251227 | 15922020 | 14993377 | 11376933
8GPR0119Galpha-s-Homo sapiens-2
9GPR0263Galpha-s-Homo sapiens-4
10GPR0266Galpha-s-Homo sapiens-5
11GPR0267Galpha-s-Homo sapiens-6
12GPR0277Galpha-s-Homo sapiens-7
13GPR0278Galpha-s-Homo sapiens
14GPR0395Galpha-s-Homo sapiens-3
Family:Gbeta REFERENCES:15251227 | 15922020 | 14993377 | 11376933 | 10449730
15GPR0147Gbeta-1-Homo sapiens
16GPR0155Gbeta-2-Homo sapiens
17GPR0160Gbeta-3-Homo sapiens-1
18GPR0164Gbeta-4-Homo sapiens
19GPR0167Gbeta-5-Homo sapiens-2
20GPR0363Gbeta-3-Homo sapiens-2
21GPR0366Gbeta-5-Homo sapiens-1
22GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227 | 15922020 | 14993377 | 11376933 | 10449730
23GPR0176Ggamma-t1-Homo sapiens
24GPR0179Ggamma-2-Homo sapiens
25GPR0183Ggamma-3-Homo sapiens
26GPR0185Ggamma-4-Homo sapiens
27GPR0188Ggamma-5-Homo sapiens-2
28GPR0192Ggamma-7-Homo sapiens
29GPR0195Ggamma-8-Homo sapiens-2
30GPR0198Ggamma-10-Homo sapiens-2
31GPR0199Ggamma-11-Homo sapiens
32GPR0203Ggamma-12-Homo sapiens
33GPR0205Ggamma-13-Homo sapiens
34GPR0210Ggamma-8-Homo sapiens-1
35GPR0253Ggamma-5-Homo sapiens-1
36GPR0364Ggamma-10-Homo sapiens-1

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory