Photo Dr. Bessy Iconomidou

2002 Defended PhD thesis

1996-2002 PhD student in the Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens.
Title: "Studies of Structural Protein Organization in Extracellular Systems with Helicoidal Architecture and Analogues"
Supervisor: Professor Stavros J. Hamodrakas

1991-1995 BSc in Biology, Faculty of Biology, University of Crete.

My research interests are mainly oriented towards three biological subjects:
1. Structural studies of peptide-analogues parts of silkmoth chorion proteins, as novel self-assembled polymers with amyloid properties.
2. Structural and self-assembly studies of fibrous proteins, which form structures of physiological importance like silkmoth and fish chorion.
3. Studies of protein-chitin interactions for the formation of arthropod cuticle.

Willis, J.H., Iconomidou, V.A., Smith, R.F. and Hamodrakas, S.J. (2005) Cuticular Proteins in 'Comprehensive Insect Science', (L. I. Gilbert, K. Iatrou, and S. Gill, Eds.), Elsevier, Oxford, Vol. 4, Ch. 2:79-110.
Iconomidou, V.A., Willis, J.H. and Hamodrakas, S.J. (2005) Unique features of the structural model of hard cuticle proteins: implications for chitin-protein interactions and cross-linking in cuticle. Insect Biochem. Mol. Biol., 35(6):553-60. [Abstract] [PDF]

Hamodrakas S.J., Hoenger A., Iconomidou V.A. (2004) Amyloid fibrillogenesis of silkmoth chorion protein peptide-analogues via a liquid-crystalline intermediate phase. J Struct Biol., 145, 226-35. [Abstract] [PDF]

Magkrioti CK, Spyropoulos IC, Iconomidou VA, Willis JH, Hamodrakas SJ. (2004) cuticleDB: a relational database of Arthropod cuticular proteins. BMC Bioinformatics. 5(1):138. [Abstract] [PDF]

Iconomidou, V.A., Chryssikos, G.D., Gionis, V., Hoenger, A., Hamodrakas, S.J. (2003) FT-Raman spectroscopy as diagnostic tool of Congo red binding to amyloids. Biopolymers (Biospectroscopy), 72, 185-192 [Abstract] [PDF]

Hamodrakas S.J., Willis J.H., Iconomidou V.A. (2002) A structural model of the chitin-binding domain of cuticle proteins, Insect Biochem Mol Biol, 32, 1577-1583. [Abstract] [PDF]

Iconomidou, V. A., Chryssikos, G. D., Gionis, V., Willis, J. H. and Hamodrakas, S. J. (2001) "Soft"-cuticle protein secondary structure as revealed by FT-Raman, ATR FT-IR and CD spectroscopy, Insect Biochem. Mol. Biol., 31, 877-885. [Abstract] [PDF]

Iconomidou, V. A., Chryssikos, G. D., Gionis, V., Vriend, G., Hoenger, A. and Hamodrakas, S. J. (2001) Amyloid-like fibrils from an 18-residue peptide-analogue of a part of the central domain of the B-family of silkmoth chorion proteins, FEBS Letters, 499, 268-273. [Abstract] [PDF]

Iconomidou, V.A. and Hamodrakas, S.J. (2001) Amyloid-like fibrils from a peptide-analogue of the central domain of silkmoth chorion proteins in "Self-Assembling Peptide Systems in Biology, Medicine, and Engineering" (A. Aggeli, N. Boden, S, Zhang, Eds.), Kluwer Press.

Iconomidou, V. A.; Vriend, G.A. and Hamodrakas, S. J. (2000) Amyloids protect the silkmoth oocyte and embryo, FEBS Letters, 479, 141-5. [Abstract] [PDF]

Iconomidou, V. A., Chryssikos, G. D., Gionis, V., Pavlidis, M. A., Paipetis, A. and Hamodrakas, S. J. (2000) Secondary structure of chorion proteins of the teleostean fish Dentex dentex by ATR FT-IR and FT-Raman spectroscopy, J. Struct. Biol., 132, 112-122. [Abstract] [PDF]

Iconomidou, V. A., Willis, J. H. and Hamodrakas, S. J. (1999) Is beta-pleated sheet the molecular conformation which dictates formation of helicoidal cuticle? Insect Biochem. Mol. Biol., 29(3), 285-92. [Abstract] [PDF]