gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0846 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY GLYCOPROTEIN HORMONE RECEPTOR
SUBFAMILY FSH RECEPTOR

Cross References:
UniProt P23945 | Q16225 | Q4QRJ3 EMBL M65085 | S59900 | M95489 | AY429104 | BC096831 | BC118548 | X68044 | S73199 | S73526
InterPro IPR002272 | IPR000276 | IPR002131 | IPR001611 | IPR000372 PDB 1XUN | 1XWD GPCRDB fshr_human
MIM 136435 | 233300 | 608115
PRINTS PR01143 | PR00373 | PR00237 PFAM PF00001 | PF00560 | PF01462

Details:
NAME GLYCOPROTEIN HORMONE RECEPTOR_FSH RECEPTOR_Homo sapiens
DESCRIPTION Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE FSHR | LGR1
SEQUENCE 
MALLLVSLLAFLSLGSGCHHRICHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRV
IQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLP
NLQYLLISNTGIKHLPDVHKIHSLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKN
GIQEIHNCAFNGTQLDELNLSDNNNLEELPNDVFHGASGPVILDISRTRIHSLPSYGLEN
LKKLRARSTYNLKKLPTLEKLVALMEASLTYPSHCCAFANWRRQISELHPICNKSILRQE
VDYMTQTRGQRSSLAEDNESSYSRGFDMTYTEFDYDLCNEVVDVTCSPKPDAFNPCEDIM
GYNILRVLIWFISILAITGNIIVLVILTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIAS
VDIHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLDCK
VQLRHAASVMVMGWIFAFAAALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSLLVLNVL
AFVVICGCYIHIYLTVRNPNIVSSSSDTRIAKRMAMLIFTDFLCMAPISFFAISASLKVP
LITVSKAKILLVLFHPINSCANPFLYAIFTKNFRRDFFILLSKCGCYEMQAQIYRTETSS
TVHNTHPRNGHCSSAPRVTNGSTYILVPLSHLAQN
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:9139796
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1
Family:Gs REFERENCES:9139796
8GPR0119Galpha-s-Homo sapiens-2
9GPR0263Galpha-s-Homo sapiens-4
10GPR0266Galpha-s-Homo sapiens-5
11GPR0267Galpha-s-Homo sapiens-6
12GPR0277Galpha-s-Homo sapiens-7
13GPR0278Galpha-s-Homo sapiens
14GPR0395Galpha-s-Homo sapiens-3

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory