gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0082 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-2B

Cross References:
UniProt P41595 | Q53TI1 | Q62221 | Q6P523 EMBL X77307 | Z36748 | AF156160 | AF156158 | AF156159 | AY136751 | AC009407 | BC063123
InterPro IPR000482 | IPR002231 | IPR000276 GPCRDB 5ht2b_human
GENEID 3357 MIM 601122
PRINTS PR00651 | PR01101 | PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-2B_Homo sapiens
DESCRIPTION 5-hydroxytryptamine receptor 2B (5-HT-2B) (Serotonin receptor 2B).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE HTR2B
SEQUENCE
MALSYRVSELQSTIPEHILQSTFVHVISSNWSGLQTESIPEEMKQIVEEQGNKLHWAALL
ILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEAM
WPLPLVLCPAWLFLDVLFSTASIMHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVW
LISIGIAIPVPIKGIETDVDNPNNITCVLTKERFGDFMLFGSLAAFFTPLAIMIVTYFLT
IHALQKKAYLVKNKPPQRLTWLTVSTVFQRDETPCSSPEKVAMLDGSRKDKALPNSGDET
LMRRTSTIGKKSVQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCNQTTLQM
LLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYRATKSVKTLRKRSSKIYFRNP
MAENSKFFKKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLLTENEGDKTEEQVSY
V
FRAGMENT NO

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Scaffold:
TYPE MUPP1( multiple activated protein kinase 1) REFERENCES 11150294
TYPE nNOS( neuronal nitric oxide synthase) NOS1 REFERENCES 10734074

Coupling with G-proteins:
Family:Gq/11 REFERENCES:8786115
1GPR0002Galpha-q-Homo sapiens-2
2GPR0029Galpha-11-Homo sapiens
3GPR0237Galpha-q-Homo sapiens-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory