gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0801 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY DOPAMINE RECEPTOR
SUBFAMILY D4

Cross References:
UniProt P51436 | O35838 EMBL U19880 | S80929 | S80920 | S80927 | S80928 | BC016086
InterPro IPR002185 | IPR000929 | IPR000276 GPCRDB drd4_mouse
GENEID 13491
PRINTS PR00569 | PR00242 | PR00237 PFAM PF00001

Details:
NAME DOPAMINE RECEPTOR_D4_Mus musculus
DESCRIPTION D(4) dopamine receptor (Dopamine D4 receptor) (D(2C) dopaminereceptor).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Drd4
SEQUENCE
MGNSSATEDGGLLAGRGPESLGTGAGLGGAGAAALVGGVLLIGLVLAGNSLVCVSVASER
TLQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASI
FNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVASPVVCGLNDVPGRDPAVC
CLENRDYVVYSSVCSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPV
SDPTQGPFFPDCPPPLPSLRTSPSDSSRPESELSQRPCSPGCLLADAALPQPPEPSSRRR
RGAKITGRERKAMRVLPVVVGAFLVCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVN
SALNPIIYTIFNAEFRSVFRKTLRLRC
FRAGMENT NO

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Scaffold:
TYPE GASP( GPCR associated sorting protein) REFERENCES 12142540
TYPE Nck Grb2 Abl Crk p85a c-Src REFERENCES 9843378

Coupling with G-proteins:
Family:Gi/o REFERENCES:1840645
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus


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Biophysics
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Laboratory