gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0743 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHOLECYSTOKININ AND GASTRIN RECEPTOR
SUBFAMILY CCK2

Cross References:
UniProt P56481 EMBL AF019371 | AF264178 | AF264177 | AK028325
InterPro IPR009126 | IPR000314 | IPR000276 GPCRDB gasr_mouse
GENEID 12426
PRINTS PR01822 | PR00527 | PR00237 PFAM PF00001

Details:
NAME CHOLECYSTOKININ AND GASTRIN RECEPTOR_CCK2_Mus musculus
DESCRIPTION Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR)(Cholecystokinin-2 receptor) (CCK2-R).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Cckbr
SEQUENCE
MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITL
YAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWL
LSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGL
ISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCY
VQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANT
WRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPR
ARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 11673456
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 11673456

Coupling with G-proteins:
Family:Gq/11 REFERENCES:1280419
1GPR0031Galpha-11-Mus musculus-2
2GPR0240Galpha-q-Mus musculus
3GPR0360Galpha-11-Mus musculus-1


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athina University of Athens
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Biophysics
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Laboratory