gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0730 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOTACTIC PEPTIDE RECEPTOR
SUBFAMILY FMLP

Cross References:
UniProt P33766 EMBL L22181
InterPro IPR015691 | IPR000826 | IPR000276 GPCRDB fpr1_mouse
GENEID 14293
PRINTS PR00526 | PR00237 PFAM PF00001

Details:
NAME CHEMOTACTIC PEPTIDE RECEPTOR_FMLP_Mus musculus
DESCRIPTION fMet-Leu-Phe receptor (fMLP receptor) (N-formyl peptide receptor)(FPR) (N-formylpeptide chemoattractant receptor).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Fpr1
SEQUENCE
MDTNMSLLMNKSAVNLMNVSGSTQSVSAGYIVLDVFSYLIFAVTFVLGVLGNGLVIWVAG
FRMKHTVTTISYLNLAIADFCFTSTLPFYIASMVMGGHWPFGWFMCKFIYTVIDINLFGS
VFLIALIALDRCICVLHPVWAQNHRTVSLAKKVIIVPWICAFLLTLPVIIRLTTVPNSRL
GPGKTACTFDFSPWTKDPVEKRKVAVTMLTVRGIIRFIIGFSTPMSIVAICYGLITTKIH
RQGLIKSSRPLRVLSFVVAAFFLCWCPFQVVALISTIQVRERLKNMTPGIVTALKITSPL
AFFNSCLNPMLYVFMGQDFRERLIHSLPASLERALTEDSAQTSDTGTNLGTNSTSLSENT
LNAM
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:11160182
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus
6GPR0129Galpha-z-Mus musculus


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athina University of Athens
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Biophysics
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Laboratory