gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0691 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOKINE RECEPTOR (CX3C)
SUBFAMILY CXCR5

Cross References:
UniProt Q04683 EMBL X71788 | L20332
InterPro IPR000248 | IPR001053 | IPR000276 GPCRDB cxcr5_mouse
PRINTS PR00241 | PR00564 | PR00237 PFAM PF00001

Details:
NAME CHEMOKINE RECEPTOR (CX3C)_CXCR5_Mus musculus
DESCRIPTION C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphomareceptor 1 homolog) (CD185 antigen).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Blr1 | Cxcr5 | Gpcr6
SEQUENCE
MNYPLTLDMGSITYNMDDLYKELAFYSNSTEIPLQDSNFCSTVEGPLLTSFKAVFMPVAY
SLIFLLGMMGNILVLVILERHRHTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLG
TFLCKTVIALHKINFYCSSLLVACIAVDRYLAIVHAVHAYRRRRLLSIHITCTAIWLAGF
LFALPELLFAKVGQPHNNDSLPQCTFSQENEAETRAWFTSRFLYHIGGFLLPMLVMGWCY
VGVVHRLLQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLERLKAVNSSCELSG
YLSVAITLCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCAGPASLCQLFPNWRKS
SLSESENATSLTTF
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:11882900
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus


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athina University of Athens
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Biophysics
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Laboratory