gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0066 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-2A

Cross References:
UniProt P35363 EMBL S49542
InterPro IPR000455 | IPR002231 | IPR000276 GPCRDB 5ht2a_mouse
GENEID 15558
PRINTS PR00516 | PR01101 | PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-2A_Mus musculus
DESCRIPTION 5-hydroxytryptamine receptor 2A (5-HT-2A) (Serotonin receptor 2A) (5-HT-2).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Htr2a | Htr2
SEQUENCE
MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYK
SSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
FRAGMENT NO

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Scaffold:
TYPE JAK2( Janus kinase) REFERENCES 9169451
TYPE MUPP1( multiple activated protein kinase 1) REFERENCES 11150294
TYPE PSD95( postsynaptic density protein) REFERENCES 12682061

Coupling with G-proteins:
Family:Gq/11 REFERENCES:1765383
1GPR0031Galpha-11-Mus musculus-2
2GPR0240Galpha-q-Mus musculus
3GPR0360Galpha-11-Mus musculus-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory