| Details: |
| NAME |
ANGIOTENSIN RECEPTOR_AT1_Homo sapiens-2 |
| DESCRIPTION |
Type-1 angiotensin II receptor (AT1) (AT1AR) (AT1BR). |
| SPECIES |
Homo sapiens |
COMMON NAME |
Human |
NCBI Taxonomy |
9606 |
| GENE |
AGTR1 | AGTR1A | AGTR1B | AT2R1 | AT2R1B |
| SEQUENCE |
MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
functional complementation
|
REFERENCES |
8576145
|
| HETERODIMER INFORMATION |
Forms heterodimer with AT2 Receptor. After the dimerization the AT2 receptor antagonizes function of the AT1 receptor
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11507095
|
| HETERODIMER INFORMATION |
Forms heterodimer with Bradykinin B2 Receptor. Dimerization results in increased signalling activity
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10993080
|
| Scaffold: |
| TYPE |
eNOS( endothelial nitric oxide synthase) /cNOS/NOS3
|
REFERENCES |
12842859
|
| TYPE |
JAK2( Janus kinase)
|
REFERENCES |
9287353
|
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
