| Details: |
| NAME |
ADRENOCEPTOR (B-ADRENOCEPTOR)_B2(Adrenoceptor)_Homo sapiens-1 |
| DESCRIPTION |
Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
| SPECIES |
Homo sapiens |
COMMON NAME |
Human |
NCBI Taxonomy |
9606 |
| GENE |
ADRB2 | ADRB2R | B2AR |
| SEQUENCE |
MGQPGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
10725388 | 12140284
|
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10725388 | 8663163
|
| HETERODIMER INFORMATION |
Forms heterodimers with delta Opioid Receptors. Heterodimerization results in altered internalization and MAPK signalling
|
METHOD |
Immunoprecipitation, Bioluminescence Resonance Energy Transfer (BRET), Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)
|
REFERENCES |
11134510 | 11278447
|
| HETERODIMER INFORMATION |
Forms heterodimers with kappa Opioid Receptors. Heterodimerization results in altered internalization and MAPK signalling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11134510
|
| HETERODIMER INFORMATION |
Forms heterodimers with B1 Adrenoceptors. Dimerization results in inhibiting internalization and ERK activation by B2 Adrenoceptor
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12244098
|
| HETERODIMER INFORMATION |
Forms heterodimers with B1 Adrenoceptors. Dimerization results in inhibiting internalization and ERK activation by B2 Adrenoceptor
|
METHOD |
Immunoprecipitation
|
REFERENCES |
12140284
|
| Scaffold: |
| TYPE |
AKAP250( A-kinase anchoring protein 250) /gravin
|
REFERENCES |
11309381
|
| TYPE |
AKAP79( A-kinase anchoring protein 79)
|
REFERENCES |
10753752 | 1127846
|
| TYPE |
GASP( GPCR associated sorting protein)
|
REFERENCES |
12142540
|
| TYPE |
NHERF1( Na+/H+ exchange regulatory factor) /EBP50( ezrin-radixin-moesin binding phosphoprotein 50-kD protein)
|
REFERENCES |
10499588 | 9671706 | 9560162
|
| TYPE |
NHERF2/E3 KARP
|
REFERENCES |
9560162
|
| TYPE |
NSF( N-ethylmaleimide-sensitive factor)
|
REFERENCES |
11278469
|
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
