gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0301 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADRENOCEPTOR (A2-ADRENOCEPTOR)
SUBFAMILY A2C(Adrenoceptor)

Cross References:
UniProt Q01337 EMBL M99376 | M97516
InterPro IPR015695 | IPR000735 | IPR002233 | IPR000276 GPCRDB ada2c_mouse
GENEID 100045767 | 11553
PRINTS PR01103 | PR00560 | PR00237 PFAM PF00001

Details:
NAME ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2C(Adrenoceptor)_Mus musculus
DESCRIPTION Alpha-2C adrenergic receptor (Alpha-2C adrenoceptor) (Alpha-2Cadrenoreceptor) (Alpha-2 adrenergic receptor subtype C4).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Adra2c
SEQUENCE
MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWVPPPGQYSAGAVAGLAAVVGF
LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
VISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
TRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRR
GGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRAR
SSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFW
IGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
FRAGMENT NO

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Scaffold:
TYPE 16-3-3 ksi REFERENCES 10224112
TYPE Spinophilin/neurabin II REFERENCES 11154706

Coupling with G-proteins:
Family:Gi/o REFERENCES:2842764
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory