gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2792 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY MELANIN-CONCENTRATING HORMONE RECEPTOR
SUBFAMILY MCHR2

Cross References:
UniProt Q969V1 | Q5VTV7 | Q6Q377 | Q9BXA8 EMBL AB060151 | AY029596 | AF399937 | AF347063 | AB058849 | AY562946 | AL590725 | BC095515
InterPro IPR000276 | IPR008362 | IPR008361 GPCRDB mchr2_human
GENEID 84539 MIM 606111
PRINTS PR00237 | PR01784 | PR01783 PFAM PF00001

Details:
NAME MELANIN-CONCENTRATING HORMONE RECEPTOR_MCHR2_Homo sapiens
DESCRIPTION Melanin-concentrating hormone receptor 2 (MCH receptor 2) (MCHR-2)(MCH-R2) (MCH2R) (MCH-2R) (MCH2) (G-protein coupled receptor 145)(GPRv17).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE MCHR2 | GPR145 | SLT
SEQUENCE
MNPFHASCWNTSAELLNKSWNKEFAYQTASVVDTVILPSMIGIICSTGLVGNILIVFTII
RSRKKTVPDIYICNLAVADLVHIVGMPFLIHQWARGGEWVFGGPLCTIITSLDTCNQFAC
SAIMTVMSVDRYFALVQPFRLTRWRTRYKTIRINLGLWAASFILALPVWVYSKVIKFKDG
VESCAFDLTSPDDVLWYTLYLTITTFFFPLPLILVCYILILCYTWEMYQQNKDARCCNPS
VPKQRVMKLTKMVLVLVVVFILSAAPYHVIQLVNLQMEQPTLAFYVGYYLSICLSYASSS
INPFLYILLSGNFQKRLPQIQRRATEKEINNMGNTLKSHF
FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:11274220 | 11355873 | 11562423
1GPR0002Galpha-q-Homo sapiens-2
2GPR0029Galpha-11-Homo sapiens
3GPR0237Galpha-q-Homo sapiens-1


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athina University of Athens
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Biophysics
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Laboratory