gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2791 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY MELANIN-CONCENTRATING HORMONE RECEPTOR
SUBFAMILY MCHR1

Cross References:
UniProt Q99705 | Q5R3J1 | Q96S47 | Q9BV08 EMBL AB063174 | AF490537 | BT006725 | CR456497 | AY562945 | Z86090 | BC001736 | BC021146 | U71092
InterPro IPR000276 | IPR004047 | IPR008361 GPCRDB mchr1_human
GENEID 2847 MIM 601751
PRINTS PR00237 | PR01507 | PR01783 PFAM PF00001

Details:
NAME MELANIN-CONCENTRATING HORMONE RECEPTOR_MCHR1_Homo sapiens
DESCRIPTION Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCHR-1)(MCH-R1) (MCH1R) (MCH-1R) (MCHR) (G-protein coupled receptor 24)(Somatostatin receptor-like protein) (SLC-1).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE MCHR1 | GPR24 | SLC1
SEQUENCE
MSVGAMKKGVGRAVGLGGGSGCQATEEDPLPNCGACAPGQGGRRWRLPQPAWVEGSSARL
WEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSPPRTGSISYINIIMPSVFGTIC
LLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHF
GETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALS
FISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVRI
LQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVY
LYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRAVSNAQTADEERTESK
GT
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:10559938
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1
Family:Gq/11 REFERENCES:10559938
8GPR0002Galpha-q-Homo sapiens-2
9GPR0029Galpha-11-Homo sapiens
10GPR0237Galpha-q-Homo sapiens-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory