gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2732 ::
CLASS FRIZZLED/SMOOTHENED
FAMILY FRIZZLED
SUBFAMILY Frizzled-1

Cross References:
UniProt Q9UP38 | O94815 | Q549T8 EMBL AF072872 | AB017363 | AC084381 | BC051271
InterPro IPR000539 | IPR000024 | IPR015526 | IPR000832 GPCRDB fzd1_human
GENEID 8321 MIM 603408
PRINTS PR00489 PFAM PF01534 | PF01392

Details:
NAME FRIZZLED_Frizzled-1_Homo sapiens
DESCRIPTION Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE FZD1
SEQUENCE 
MAEEEAPKKSRAAGGGASWELCAGALSARLAEEGSGDAGGRRRPPVDPRRLARQLLLLLW
LLEAPLLLGVRAQAAGQGPGQGPGPGQQPPPPPQQQQSGQQYNGERGISVPDHGYCQPIS
IPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVL
EQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTP
SLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFSCPRALKVPSYLNYHFLGEKDCGAPC
EPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSG
CYTAVAVAYIAGFLLEDRVVCNDKFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWW
VILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVG
LNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVF
SVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPDF
TVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:11563835
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1
Family:Gq/11 REFERENCES:11563835
8GPR0002Galpha-q-Homo sapiens-2
9GPR0029Galpha-11-Homo sapiens
10GPR0237Galpha-q-Homo sapiens-1

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory