gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2731 ::
CLASS FRIZZLED/SMOOTHENED
FAMILY FRIZZLED
SUBFAMILY Frizzled-1

Cross References:
UniProt O57328 | Q9IA07 EMBL AF031830 | AF224314
InterPro IPR000539 | IPR000024 | IPR015526 | IPR000832 GPCRDB fzd1_chick
GENEID 374062
PRINTS PR00489 PFAM PF01534 | PF01392

Details:
NAME FRIZZLED_Frizzled-1_Gallus gallus
DESCRIPTION Frizzled-1 precursor (Fz-1) (cFz-1).
SPECIES Gallus gallus COMMON NAME Chicken NCBI Taxonomy 9031
GENE FZD1 | FZ1
SEQUENCE
MAERRGPAGGGSGEVGGGRRAGGDRCPRRPPALPLLLLLWAAALPAGGQPAAQPAALSER
GISIPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELK
FFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLRCEKFPVHGAGEL
CVGQNASERGTPTPALRPESWTSNPHRGGGAGGSGPGEARGRFSCPRALKVPSYLNYRFL
GEKDCGAPCEPGRLYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMKRFSYP
ERPIIFLSGCYTAVAVAYIAGFLLEERVVCNERFAEDGSRTVAQGTKREGCTILFMMLYF
FGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGD
VLSGVCFVGINNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLE
KLMVRIGIFSVLYTVPATIVIACYFYEQAFREQWERSWVTQSCKSYAIPCPNNHSSHHPP
MSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:11563835
1GPR0217Galpha-i1-Gallus gallus
2GPR0225Galpha-i2-Gallus gallus
Family:Gq/11 REFERENCES:11563835
3GPR0003Galpha-11-Gallus gallus


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory