gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2615 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY PARATHYROID HORMONE RECEPTOR
SUBFAMILY PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR

Cross References:
UniProt Q03431 | Q2M1U3 EMBL L04308 | X68596 | U22409 | U22401 | U22402 | U22403 | U22404 | U22405 | U22406 | U22407 | U22408 | U17418 | AY449732 | BC112221 | BC112247
InterPro IPR001879 | IPR002170 | IPR000832 PDB 1BL1 | 1ET2 | 1ET3 GPCRDB pthr1_human
GENEID 5745 MIM 156400 | 166000 | 168468 | 215045 | 600002
PRINTS PR00249 | PR00393 PFAM PF00002 | PF02793

Details:
NAME PARATHYROID HORMONE RECEPTOR_PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR_Homo sapiens
DESCRIPTION Parathyroid hormone/parathyroid hormone-related peptide receptorprecursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE PTHR1 | PTHR
SEQUENCE
MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPA
SIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPL
GAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETRE
REVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVK
DAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWIL
VEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK
WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVH
YIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLA
LDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKP
GTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM
FRAGMENT NO

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Coupling with G-proteins:
Family:Gs REFERENCES:1658941
1GPR0119Galpha-s-Homo sapiens-2
2GPR0263Galpha-s-Homo sapiens-4
3GPR0266Galpha-s-Homo sapiens-5
4GPR0267Galpha-s-Homo sapiens-6
5GPR0277Galpha-s-Homo sapiens-7
6GPR0278Galpha-s-Homo sapiens
7GPR0395Galpha-s-Homo sapiens-3


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory