gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2606 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY GROWTH HORMONE RELEASING PEPTIDES RECEPTOR
SUBFAMILY Growth hormone secretagogue receptor type 1(Ghrelin receptor)

Cross References:
UniProt Q92847 | Q14D12 | Q92848 | Q96RJ7 EMBL U60179 | U60181 | AF369786 | AF369786 | AY429112 | AY322544 | BC113547
InterPro IPR003905 | IPR000276 GPCRDB ghsr_human
GENEID 2693 MIM 601898 | 604271
PRINTS PR01417 | PR00237 PFAM PF00001

Details:
NAME GROWTH HORMONE RELEASING PEPTIDES RECEPTOR_Growth hormone secretagogue receptor type 1(Ghrelin receptor)_Homo sapiens
DESCRIPTION Growth hormone secretagogue receptor type 1 (GHS-R) (GH-releasingpeptide receptor) (GHRP) (Ghrelin receptor).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE GHSR
SEQUENCE
MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT
ESSINT
FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:8688086
1GPR0002Galpha-q-Homo sapiens-2
2GPR0029Galpha-11-Homo sapiens
3GPR0237Galpha-q-Homo sapiens-1


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athina University of Athens
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Biophysics
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Laboratory