gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2586 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY CORTICOTROPIN-RELEASING FACTOR RECEPTOR
SUBFAMILY CRF1

Cross References:
UniProt P34998 | Q13008 | Q9UK64 EMBL L23333 | L23332 | X72304 | AF039523 | AF039510 | AF039511 | AF039512 | AF039513 | AF039514 | AF039515 | AF039516 | AF039517 | AF039518 | AF039519 | AF039520 | AF039521 | AF039522 | U16273 | AF180301 | AY457172
InterPro IPR003052 | IPR003051 | IPR001879 | IPR000832 GPCRDB crfr1_human
MIM 122561
PRINTS PR01279 | PR01280 | PR00249 PFAM PF00002 | PF02793

Details:
NAME CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF1_Homo sapiens
DESCRIPTION Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1)(Corticotropin-releasing hormone receptor 1) (CRH-R 1).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CRHR1 | CRFR | CRFR1 | CRHR
SEQUENCE
MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA
GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV
IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLR
NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC
YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI
YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF
VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV
ARAMSIPTSPTRVSFHSIKQSTAV
FRAGMENT NO

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Coupling with G-proteins:
Family:Gs REFERENCES:1280419
1GPR0119Galpha-s-Homo sapiens-2
2GPR0263Galpha-s-Homo sapiens-4
3GPR0266Galpha-s-Homo sapiens-5
4GPR0267Galpha-s-Homo sapiens-6
5GPR0277Galpha-s-Homo sapiens-7
6GPR0278Galpha-s-Homo sapiens
7GPR0395Galpha-s-Homo sapiens-3


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory