gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2566 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY VASOPRESSIN AND OXYTOCIN RECEPTOR
SUBFAMILY V2

Cross References:
UniProt P48044 EMBL X83741
InterPro IPR000276 | IPR001817 | IPR000161 GPCRDB v2r_bovin
GENEID 281642
PRINTS PR00237 | PR00896 | PR00898 PFAM PF00001

Details:
NAME VASOPRESSIN AND OXYTOCIN RECEPTOR_V2_Bos taurus
DESCRIPTION Vasopressin V2 receptor (Renal-type arginine vasopressin receptor)(Antidiuretic hormone receptor) (AVPR V2).
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
GENE AVPR2
SEQUENCE
MFMASTTSAVPWHLSQPTPAGNGSEGELLTARDPLLAQAELALLSTVFVAVALSNGLVLG
ALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAHRHGGGTHWNRPVLLAWAFSLLFSLPQLFIFAQ
RDVDGSGVLDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLGPGPV
PRAGGPRRGCRPGSPAEGARVSAAVAKTVKMTLVIVIVYVLCWAPFFLVQLWAAWDPEAP
REGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCTWRRAPPSPGPQEESCATA
SSFLAKDTPS
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12554793
HETERODIMER INFORMATION Forms functional heterodimers with OT Receptors METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12554793
HETERODIMER INFORMATION Forms functional heterodimers with V1A Receptors METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12554793

Coupling with G-proteins:
Family:Gs REFERENCES:1534150
1GPR0114Galpha-s-Bos taurus


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