| Details: |
| NAME |
SOMATOSTATIN RECEPTOR_SST2_Mus musculus |
| DESCRIPTION |
Somatostatin receptor type 2 (SS2R) (SRIF-1). |
| SPECIES |
Mus musculus |
COMMON NAME |
Mouse |
NCBI Taxonomy |
10090 |
| GENE |
Sstr2 | Smstr2 | Sst2 |
| SEQUENCE |
MEMSSEQLNGSQVWVSSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCG
NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT
VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWCVSLLVILPIMIY
AGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGI
RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVIL
TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTEDGERSDSKQDKSRLNETTETQRTL
LNGDLQTSI
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HETERODIMER INFORMATION |
Forms heterodimer with SST3 Receptor. Dimerization results in inactivation of SST3 Receptor function
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11134004
|
| HETERODIMER INFORMATION |
Forms heterodimers with MU OPIOID RECEPTORS. Dimerization results in cross-modulation of receptor phosphorylation, internalization and desensitization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11896051
|
| Scaffold: |
| TYPE |
Shank1/SSTRIP( somatostatin receptor interacting protein) /synamon
|
REFERENCES |
10551867
|
| TYPE |
Shank2/ProSAP1( proline-rich synapse-associated protein 1) /CortBP1
|
REFERENCES |
10373412
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 7622071 | | 1 | GPR0021 | Galpha-o1-Mus musculus | | 2 | GPR0227 | Galpha-i2-Mus musculus-2 | | 3 | GPR0289 | Galpha-i1-Mus musculus | | 4 | GPR0331 | Galpha-i2-Mus musculus-1 | | 5 | GPR0385 | Galpha-i3-Mus musculus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
