gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2378 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY P2Y RECEPTOR
SUBFAMILY P2Y1

Cross References:
UniProt Q9BXA5 | Q8TDQ8 EMBL AF348078 | AF247785 | BC030948
InterPro IPR000276 | IPR002286 GPCRDB sucr1_human
GENEID 56670 MIM 606381
PRINTS PR00237 | PR01157 PFAM PF00001

Details:
NAME P2Y RECEPTOR_P2Y1_Homo sapiens-1
DESCRIPTION Succinate receptor 1 (G-protein coupled receptor 91) (P2Y purinoceptor1-like).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE SUCNR1 | GPR91
SEQUENCE
MAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFN
LSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLII
KYPFREHLLQKKEFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYN
LIYSMCLTLLGFLIPLFVMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVL
FTPYHVMRNVRIASRLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRD
MLMNQLRHNFKSLTSFSRWAHELLLSFREK
FRAGMENT NO

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Dimerization:
HETERODIMER INFORMATION Forms heterodimers with Adenosine A1 Receptor. Heterodimerization results in altered ligand binding METHOD Immunoprecipitation, Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 11390975 | 12417330 | 12123822

Scaffold:
TYPE NHERF1( Na+/H+ exchange regulatory factor) /EBP50( ezrin-radixin-moesin binding phosphoprotein 50-kD protein) REFERENCES 9671706

Coupling with G-proteins:
Family:Gq/11 REFERENCES:8159738
1GPR0002Galpha-q-Homo sapiens-2
2GPR0029Galpha-11-Homo sapiens
3GPR0237Galpha-q-Homo sapiens-1


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