gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2365 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY OREXIN RECEPTOR
SUBFAMILY Orexin 1

Cross References:
UniProt O43613 EMBL AF041243
InterPro IPR000276 | IPR000204 | IPR004059 GPCRDB ox1r_human
GENEID 3061 MIM 602392
PRINTS PR00237 | PR01521 | PR01064 PFAM PF00001

Details:
NAME OREXIN RECEPTOR_Orexin 1_Homo sapiens
DESCRIPTION Orexin receptor type 1 (Ox1r) (Hypocretin receptor type 1).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE HCRTR1
SEQUENCE
MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRGRAFLAEVKQMRARRKTAKML
MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
TTVLP
FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:9491897
1GPR0002Galpha-q-Homo sapiens-2
2GPR0029Galpha-11-Homo sapiens
3GPR0237Galpha-q-Homo sapiens-1


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athina University of Athens
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Biophysics
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Laboratory