Details: |
NAME |
OPIOID AND OPIOID-LIKE RECEPTOR_MU OPIOID PEPTIDE (MOR)_Mus musculus-4 |
DESCRIPTION |
Mu opioid receptor . |
SPECIES |
Mus musculus |
COMMON NAME |
Mouse |
NCBI Taxonomy |
10090 |
GENE |
Oprm1 | Mor |
SEQUENCE |
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSI FTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSI DCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNL RRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVL YAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQ
|
FRAGMENT |
YES
|
|
|
|
Homepage
|
Dimerization: |
HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12217652
|
HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10842167
|
HETERODIMER INFORMATION |
Forms heterodimers with delta Opioid Peptide Receptor. Dimerization results in Changing the binding properties of opiate ligands and altered G-protein coupling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10842167 | 11069979
|
HETERODIMER INFORMATION |
Forms heterodimers with SST2 RECEPTORS. Dimerization results in cross-modulation of receptor phosphorylation, internalization and desensitization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11896051
|
Coupling with G-proteins: |
Family:Gi/o |
REFERENCES: | 8393525 | 1 | GPR0021 | Galpha-o1-Mus musculus | 2 | GPR0227 | Galpha-i2-Mus musculus-2 | 3 | GPR0289 | Galpha-i1-Mus musculus | 4 | GPR0331 | Galpha-i2-Mus musculus-1 | 5 | GPR0385 | Galpha-i3-Mus musculus |
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