| Details: |
| NAME |
OPIOID AND OPIOID-LIKE RECEPTOR_DELTA OPIOID PEPTIDE (DOR)_Mus musculus |
| DESCRIPTION |
Delta-type opioid receptor (DOR-1) (K56) (MSL-2). |
| SPECIES |
Mus musculus |
COMMON NAME |
Mouse |
NCBI Taxonomy |
10090 |
| GENE |
Oprd1 |
| SEQUENCE |
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTAC
TPSDGPGGGAAA
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET), Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)
|
REFERENCES |
12217652 | 11278447
|
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
9341132 | 10842167
|
| HETERODIMER INFORMATION |
Forms heterodimers with kappa Opioid Peptide Receptor. Dimerization results in altered ligand binding, potentiated signalling and altered internalization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10385123
|
| HETERODIMER INFORMATION |
Forms heterodimers with mu Opioid Peptide Receptor. Dimerization results in Changing the binding properties of opiate ligands and altered G-protein coupling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10842167 | 11069979
|
| HETERODIMER INFORMATION |
Forms heterodimers with B2 Adrenoceptors. Heterodimerization results in altered internalization and MAPK signalling
|
METHOD |
Immunoprecipitation, Bioluminescence Resonance Energy Transfer (BRET), Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)
|
REFERENCES |
11134510 | 11278447
|
| Scaffold: |
| TYPE |
GASP( GPCR associated sorting protein)
|
REFERENCES |
12142540
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 1335167 | | 1 | GPR0021 | Galpha-o1-Mus musculus | | 2 | GPR0227 | Galpha-i2-Mus musculus-2 | | 3 | GPR0289 | Galpha-i1-Mus musculus | | 4 | GPR0331 | Galpha-i2-Mus musculus-1 | | 5 | GPR0385 | Galpha-i3-Mus musculus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
