gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0018 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-1A

Cross References:
UniProt Q98998 EMBL Y07901
InterPro IPR000610 | IPR002231 | IPR000276 GPCRDB 5ht1a_xenla
GENEID 378605
PRINTS PR00512 | PR01101 | PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-1A_Xenopus laevis
DESCRIPTION 5-hydroxytryptamine receptor 1A (5-HT-1A) (Serotonin receptor 1A) (5-HT1A) (X5-HT1A).
SPECIES Xenopus laevis COMMON NAME African clawed frog NCBI Taxonomy 8355
GENE htr1a
SEQUENCE
MDASNNTTSWNILQRGRMGPSWRRCPVSYQIIASLFLGRSFSAGIFGNACVIAAIALERS
LQNVANYLIGSLAVTDLMVSVLVLPMAAQNQVLNKWTLGQVTCDIFISLDVLCCTSSILH
LCAIALDRYWAITDPIDYVNKRTPRRAAVLISITWIVGFSISIPPMLGWRTPEDRSDPNA
CRISEDPGYTIYSTFGAFYIPLILMLVLYGKIFKAARFRIRKTVKKAEKKKVADTCLSVS
QQSPKEKQRGAQQELEEVGGAQAQRCVNGAIRHGEEGAVLEIIEVHHYVNSKCHLHCKPV
PPPEQLPPALKNDRATEAKRKVALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCET
CHMPHLLFDIITWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCKFCRQ
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:3138543
1GPR0016Galpha-o-Xenopus laevis
2GPR0112Galpha-i3-Xenopus laevis
3GPR0222Galpha-i1-Xenopus laevis
4GPR0271Galpha-o1-Xenopus laevis
5GPR0272Galpha-i-Xenopus laevis


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athina University of Athens
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