gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0016 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-1A

Cross References:
UniProt Q64264 | Q60956 | Q61617 EMBL U39391 | U33820 | L20339
InterPro IPR000610 | IPR002231 | IPR000276 GPCRDB 5ht1a_mouse
PRINTS PR00512 | PR01101 | PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-1A_Mus musculus
DESCRIPTION 5-hydroxytryptamine receptor 1A (5-HT-1A) (Serotonin receptor 1A) (5-HT1A).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Htr1a | Gpcr18
SEQUENCE
MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRAPED
RSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGT
SFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGN
SKGDLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
R
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:3138543
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus


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athina University of Athens
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Biophysics
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Laboratory