gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0151 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ACETYLCHOLINE RECEPTOR (MUSCARINIC)
SUBFAMILY M4

Cross References:
UniProt P32211 | Q64056 EMBL X63473 | S74916
InterPro IPR000276 | IPR001432 | IPR000995 GPCRDB acm4_mouse
GENEID 12672
PRINTS PR00237 | PR00243 | PR00541 PFAM PF00001

Details:
NAME ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M4_Mus musculus
DESCRIPTION Muscarinic acetylcholine receptor M4 (Mm4 mAChR).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Chrm4 | Chrm-4
SEQUENCE
MANFTPVNGSSANQSVRLVTTAHNHLETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNR
QLQTVNNYFLFSLACADLIIGAFSMNLYTLYIIKGYWPLGAVVCDLWLALDYVVSNASVM
NLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVP
DNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKT
LAFLKSPLMKPSIKKPPPGGASREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSA
TQNTKERPPTELSTTEAATTPALPAPTLQPRTLNPASKWSKIQIVTKQTGSECVTAIEIV
PATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMV
LVNTFCQSCIPERVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:3037705
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory