gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0147 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ACETYLCHOLINE RECEPTOR (MUSCARINIC)
SUBFAMILY M4

Cross References:
UniProt P30544 EMBL X65865
InterPro IPR000276 | IPR001432 | IPR000995 GPCRDB acm4_xenla
PRINTS PR00237 | PR00243 | PR00541 PFAM PF00001

Details:
NAME ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M4_Xenopus laevis
DESCRIPTION Muscarinic acetylcholine receptor M4.
SPECIES Xenopus laevis COMMON NAME African clawed frog NCBI Taxonomy 8355
GENE chrm4
SEQUENCE
MENDTWENESSASNHSIDETIVEIPGKYQTMEMIFIATVTGSLSLVTVVGNILVMLSIKV
NRQLQTVNNYFLFSLACADLIIGVFSMNLYSLYIIKGYWPLGPIVCDLWLALDYVVSNAS
VMNLLIISLERXFCVTKPLTYPARRTTKMAGLMIAAAWLLSFELWAPAILFWQFIVGQRT
VPSGECYIQFLSNPAVTFGTAIAAFYLPVVIMTILYIHISLASRSRVRRHCPETRQEKKK
PISSMKSLLIKQTKNIPKQDAGDKVVEKKNGVSNGKIEKSMTNLQTAEEKETSNESSSAS
LSHNPPEKQPLSEASSGVVLAPTQSMPPLPAKANTASKWSKIKIVTKQTGNECVTAIEIV
PECAIPLPEQANNRPVNVARKFASIARNQVRKKRQMAAREKKVTRTIFAILLAFIITWTP
YNVMVLINTFCQTCIPETIWYIGYWLCYVNSTINPACYALCNATFKKTFKHLLMCQYKSI
GTAR
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:3037705
1GPR0016Galpha-o-Xenopus laevis
2GPR0112Galpha-i3-Xenopus laevis
3GPR0222Galpha-i1-Xenopus laevis
4GPR0271Galpha-o1-Xenopus laevis
5GPR0272Galpha-i-Xenopus laevis


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory