| Details: |
| NAME |
ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M3_Rattus norvegicus |
| DESCRIPTION |
Muscarinic acetylcholine receptor M3. |
| SPECIES |
Rattus norvegicus |
COMMON NAME |
Rat |
NCBI Taxonomy |
10116 |
| GENE |
Chrm3 | Chrm-3 |
| SEQUENCE |
MTLHSNSTTSPLFPNISSSWVHSPSEAGLPLGTVTQLGSYNISQETGNFSSNDTSSDPLG
GHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVIS
MNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRT
TKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFY
MPVTIMTILYWRIYKETEKRTKELAGLQASGTEAEAENFVHPTGSSRSCSSYELQQQGVK
RSSRRKYGRCHFWFTTKSWKPSAEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSET
RAIYSIVLKLPGHSSILNSTKLPSSDNLQVSNEDLGTVDVERNAHKLQAQKSMGDGDNCQ
KDFTKLPIQLESAVDTGKTSDTNSSADKTTATLPLSFKEATLAKRFALKTRSQITKRKRM
SLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNP
VCYALCNKTFRTTFKTLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10383466
|
| HETERODIMER INFORMATION |
Forms heterodimers with Muscarinic M2 Receptors. Heterodimerization results in altered internalization of the receptors
|
METHOD |
Chimeric receptor reconstitution studies
|
REFERENCES |
10490911
|
| Coupling with G-proteins: |
| Family:G12/13 |
REFERENCES: | 11036069 | | 1 | GPR0036 | Galpha-12-Rattus norvegicus | | Family:Gq/11 |
REFERENCES: | 11242080 | | 2 | GPR0032 | Galpha-11-Rattus norvegicus | | 3 | GPR0242 | Galpha-q-Rattus norvegicus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
