gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1270 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY NEUROPEPTIDE Y RECEPTOR
SUBFAMILY Y5

Cross References:
UniProt O62729 EMBL AF049328
InterPro IPR000276 | IPR000393 | IPR000611 GPCRDB npy5r_canfa
GENEID 403712
PRINTS PR00237 | PR01016 | PR01012 PFAM PF00001

Details:
NAME NEUROPEPTIDE Y RECEPTOR_Y5_Canis familiaris
DESCRIPTION Neuropeptide Y receptor type 5 (NPY5-R) (NPY-Y5 receptor) (Y5receptor) (NPYY5).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
GENE NPY5R | NPY5
SEQUENCE
MDLELQDFYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL
LILMALMRKRNQKTMVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL
QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
VELQETFDSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
GLSNKENKLEENEMINLTLQPFKKSGPQVKLSSSHKWSYSFIRKHRRRYSKKTACVLPAP
ARPPQENHSRMLPENFGSVRSQHSSSSKFIPGVPTCFEVKPEENSDVHDMRVNRSIMRIK
KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL
NPILYGFLNNGIKADLISLIQCLHMS
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Fluorescence Resonance Energy Transfer (FRET) REFERENCES 12524448

Coupling with G-proteins:
Family:Gi/o REFERENCES:8700207
1GPR0223Galpha-i2-Canis familiaris


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory