gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0121 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ACETYLCHOLINE RECEPTOR (MUSCARINIC)
SUBFAMILY M1

Cross References:
UniProt P08482 EMBL M16406 | S73971
InterPro IPR000276 | IPR002228 | IPR000995 GPCRDB acm1_rat
GENEID 25229
PRINTS PR00237 | PR00243 | PR00538 PFAM PF00001

Details:
NAME ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M1_Rattus norvegicus
DESCRIPTION Muscarinic acetylcholine receptor M1.
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Chrm1 | Chrm-1
SEQUENCE
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:10821841
1GPR0036Galpha-12-Rattus norvegicus
Family:Gq/11 REFERENCES:3037705
2GPR0032Galpha-11-Rattus norvegicus
3GPR0242Galpha-q-Rattus norvegicus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory