gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1098 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY S1P4

Cross References:
UniProt O95977 EMBL AJ000479 | AY322537 | BC014970
InterPro IPR004064 | IPR000276 | IPR004061 PDB 2DCO GPCRDB edg6_human
GENEID 8698 MIM 603751
PRINTS PR01526 | PR00237 | PR01523 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_S1P4_Homo sapiens
DESCRIPTION Sphingosine 1-phosphate receptor Edg-6 (S1P receptor Edg-6)(Endothelial differentiation G-protein coupled receptor 6)(Sphingosine 1-phosphate receptor 4) (S1P4).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE EDG6
SEQUENCE
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:10679247
1GPR0002Galpha-q-Homo sapiens-2
2GPR0029Galpha-11-Homo sapiens
3GPR0237Galpha-q-Homo sapiens-1


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athina University of Athens
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Biophysics
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