gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0101 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-6

Cross References:
UniProt P50406 | Q13640 EMBL L41147 | AY429105 | BC074995 | BC074996 | Z49119
InterPro IPR000276 GPCRDB 5ht6r_human
GENEID 3362 MIM 601109
PRINTS PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-6_Homo sapiens
DESCRIPTION 5-hydroxytryptamine receptor 6 (5-HT-6) (Serotonin receptor 6).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE HTR6
SEQUENCE
MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
FRAGMENT NO

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Coupling with G-proteins:
Family:Gs REFERENCES:8522988
1GPR0119Galpha-s-Homo sapiens-2
2GPR0263Galpha-s-Homo sapiens-4
3GPR0266Galpha-s-Homo sapiens-5
4GPR0267Galpha-s-Homo sapiens-6
5GPR0277Galpha-s-Homo sapiens-7
6GPR0278Galpha-s-Homo sapiens
7GPR0395Galpha-s-Homo sapiens-3


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory