gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0089 ::
FAMILY Ion channels
SUBFAMILY ATP-sensitive inward rectifier potassium channels
TYPE ATP-sensitive inward rectifier potassium channel 12

Cross References:
UniProt Q14500 | O43401 | Q15756 | Q8NG63 EMBL L36069 | U53143 | AB074970 | AB182123 | BC027982 | AF005214
InterPro IPR001838 | IPR003272 | IPR013521 | IPR013518 | IPR013673
PRODOM PD001103 GENEID 3768 MIM 602323
PRINTS PR01325 | PR01320 PFAM PF01007 | PF08466

Details:
NAME ATP-sensitive inward rectifier potassium channel-12-Homo sapiens
DESCRIPTION ATP-sensitive inward rectifier potassium channel 12 (Potassiumchannel, inwardly rectifying subfamily J member 12) (Inward rectifierK(+) channel Kir2.2) (Kir2.2v) (IRK2).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE KCNJ12 | IRK2 | KCNJN1
SEQUENCE 
MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
GEYIPLDQIDIDVGF
 FRAGMENT NO
FUNCTION Probably participates in establishing action potentials waveform and excitability of neuronal and muscle tissues
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 10990455
1GPR0147Gbeta-1-Homo sapiens
2GPR0155Gbeta-2-Homo sapiens
3GPR0160Gbeta-3-Homo sapiens-1
4GPR0164Gbeta-4-Homo sapiens
5GPR0167Gbeta-5-Homo sapiens-2
6GPR0363Gbeta-3-Homo sapiens-2
7GPR0366Gbeta-5-Homo sapiens-1
8GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227 | 10990455
9GPR0176Ggamma-t1-Homo sapiens
10GPR0179Ggamma-2-Homo sapiens
11GPR0183Ggamma-3-Homo sapiens
12GPR0185Ggamma-4-Homo sapiens
13GPR0188Ggamma-5-Homo sapiens-2
14GPR0192Ggamma-7-Homo sapiens
15GPR0195Ggamma-8-Homo sapiens-2
16GPR0198Ggamma-10-Homo sapiens-2
17GPR0199Ggamma-11-Homo sapiens
18GPR0203Ggamma-12-Homo sapiens
19GPR0205Ggamma-13-Homo sapiens
20GPR0210Ggamma-8-Homo sapiens-1
21GPR0253Ggamma-5-Homo sapiens-1
22GPR0364Ggamma-10-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
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