gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0822 ::
FAMILY SHC transforming proteins
SUBFAMILY SHC transforming proteins
TYPE SHC transforming protein 1

Cross References:
UniProt P29353 | O15290 | Q8N4K5 | Q96CL1 EMBL X68148 | U73377 | Y09847 | BC014158 | BC033925
InterPro IPR011993 | IPR006019 | IPR006020 | IPR000980 PDB 1MIL | 1N3H | 1OY2 | 1QG1 | 1WCP
PRODOM PD000093 GENEID 6464 MIM 600560
PRINTS PR00401 | PR00629 PFAM PF00640 | PF00017

Details:
NAME SHC transforming protein-1-Homo sapiens-2
DESCRIPTION SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2domain-containing-transforming protein C1).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE SHC1 | SHC | SHCA
SEQUENCE 
MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIDGAAMPESGPLPLLQDMNKLSGGGGR
RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
LNLMAADCKQIIANH
 FRAGMENT NO
FUNCTION Signaling adapter that couples activated growth factors receptors to signaling pathway
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 14671004 | 7568118
1GPR0147Gbeta-1-Homo sapiens
2GPR0155Gbeta-2-Homo sapiens
3GPR0160Gbeta-3-Homo sapiens-1
4GPR0164Gbeta-4-Homo sapiens
5GPR0167Gbeta-5-Homo sapiens-2
6GPR0363Gbeta-3-Homo sapiens-2
7GPR0366Gbeta-5-Homo sapiens-1
8GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227 | 14671004 | 7568118
9GPR0176Ggamma-t1-Homo sapiens
10GPR0179Ggamma-2-Homo sapiens
11GPR0183Ggamma-3-Homo sapiens
12GPR0185Ggamma-4-Homo sapiens
13GPR0188Ggamma-5-Homo sapiens-2
14GPR0192Ggamma-7-Homo sapiens
15GPR0195Ggamma-8-Homo sapiens-2
16GPR0198Ggamma-10-Homo sapiens-2
17GPR0199Ggamma-11-Homo sapiens
18GPR0203Ggamma-12-Homo sapiens
19GPR0205Ggamma-13-Homo sapiens
20GPR0210Ggamma-8-Homo sapiens-1
21GPR0253Ggamma-5-Homo sapiens-1
22GPR0364Ggamma-10-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
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