gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0651 ::
FAMILY Small GTP-binding proteins
SUBFAMILY Rho small GTPases
TYPE Rac

Cross References:
UniProt Q05144 | Q3TBC4 | Q9D8X9 EMBL X53247 | AK007561 | AK144136 | AK171321 | BC005455
InterPro IPR003578 | IPR013753 | IPR001806 | IPR005225
GENEID 19354
PRINTS PR00449 PFAM PF00071

Details:
NAME Rac-Mus musculus-4
DESCRIPTION Ras-related C3 botulinum toxin substrate 2 precursor (p21-Rac2) (EN-7protein).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Rac2
SEQUENCE
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR
DDKDTIEKLKEKKLAPITYPQGLALAKDIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ
PTRQQKRPCSLL
FRAGMENT NO
FUNCTION Plasma membrane-associated small GTPase which cycless between an active GTP-bound and inactive GDP-bound state
Interacting with G-proteins:
Family:Gi/o REFERENCES:11099498
1GPR0227Galpha-i2-Mus musculus-2
2GPR0289Galpha-i1-Mus musculus
3GPR0331Galpha-i2-Mus musculus-1
4GPR0385Galpha-i3-Mus musculus
Family:Gbeta REFERENCES:11099498 | 15251227
5GPR0148Gbeta-1-Mus musculus
6GPR0156Gbeta-2-Mus musculus
7GPR0161Gbeta-3-Mus musculus
8GPR0165Gbeta-4-Mus musculus
9GPR0168Gbeta-5-Mus musculus-2
10GPR0291unclassified_Gbeta-Mus musculus-1
11GPR0318unclassified_Gbeta-Mus musculus-2
12GPR0376Gbeta-5-Mus musculus-3
13GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:11099498 | 15251227
14GPR0178Ggamma-t1-Mus musculus
15GPR0181Ggamma-2-Mus musculus
16GPR0184Ggamma-3-Mus musculus
17GPR0186Ggamma-4-Mus musculus
18GPR0189Ggamma-5-Mus musculus
19GPR0193Ggamma-7-Mus musculus
20GPR0196Ggamma-8-Mus musculus-2
21GPR0200Ggamma-11-Mus musculus
22GPR0204Ggamma-12-Mus musculus
23GPR0206Ggamma-13-Mus musculus
24GPR0211Ggamma-8-Mus musculus-1
25GPR0349Ggamma-1-Mus musculus
26GPR0379Ggamma-10-Mus musculus


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory