gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0641 ::
FAMILY Small GTP-binding proteins
SUBFAMILY Rho small GTPases
TYPE Rac

Cross References:
UniProt P63000 | O95501 | P15154 | Q3Y4D3 | Q5JAA8 | Q9BTB4 EMBL M29870 | M31467 | AJ132694 | AJ132695 | AJ132695 | AF136373 | AY279384 | AF498964 | BT007121 | DQ165078 | AC009412 | AC009412 | BC004247 | BC050687 | BC107748
InterPro IPR003578 | IPR013753 | IPR001806 | IPR005225 PDB 1E96 | 1FOE | 1G4U | 1HE1 | 1HH4 | 1I4D | 1I4L | 1I4T | 1MH1 | 1RYF | 1RYH | 2FJU | 2H7V | 2NZ8 | 2P2L | 2RMK
GENEID 5879 MIM 602048
PRINTS PR00449 PFAM PF00071

Details:
NAME Rac-Homo sapiens-1
DESCRIPTION Ras-related C3 botulinum toxin substrate 1 precursor (p21-Rac1) (Ras-like protein TC25) (Cell migration-inducing gene 5 protein).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE RAC1 | MIG5
SEQUENCE
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
FRAGMENT NO
FUNCTION Plasma membrane-associated small GTPase which cycless between active GTP-bound and inactive GDP-bound states
Interacting with G-proteins:
Family:Gi/o REFERENCES:11099498
1GPR0109Galpha-i3-Homo sapiens
2GPR0218Galpha-i1-Homo sapiens-1
3GPR0226Galpha-i2-Homo sapiens-2
4GPR0261Galpha-i1-Homo sapiens-2
5GPR0365Galpha-i2-Homo sapiens-1
Family:Gbeta REFERENCES:11099498 | 15251227
6GPR0147Gbeta-1-Homo sapiens
7GPR0155Gbeta-2-Homo sapiens
8GPR0160Gbeta-3-Homo sapiens-1
9GPR0164Gbeta-4-Homo sapiens
10GPR0167Gbeta-5-Homo sapiens-2
11GPR0363Gbeta-3-Homo sapiens-2
12GPR0366Gbeta-5-Homo sapiens-1
13GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:11099498 | 15251227
14GPR0176Ggamma-t1-Homo sapiens
15GPR0179Ggamma-2-Homo sapiens
16GPR0183Ggamma-3-Homo sapiens
17GPR0185Ggamma-4-Homo sapiens
18GPR0188Ggamma-5-Homo sapiens-2
19GPR0192Ggamma-7-Homo sapiens
20GPR0195Ggamma-8-Homo sapiens-2
21GPR0198Ggamma-10-Homo sapiens-2
22GPR0199Ggamma-11-Homo sapiens
23GPR0203Ggamma-12-Homo sapiens
24GPR0205Ggamma-13-Homo sapiens
25GPR0210Ggamma-8-Homo sapiens-1
26GPR0253Ggamma-5-Homo sapiens-1
27GPR0364Ggamma-10-Homo sapiens-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory