gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0554 ::
FAMILY Phospholipases C
SUBFAMILY Phospholipases C beta
TYPE Phospholipase C beta 4

Cross References:
UniProt Q07722 | Q07721 | Q07723 | Q07724 EMBL L13936 | L13935 | L13937 | L13938
InterPro IPR000008 | IPR009535 | IPR011992 | IPR015359 | IPR013841 | IPR001192 | IPR000909 | IPR001711
PRODOM PD001202 GENEID 281985
PRINTS PR00360 | PR00390 PFAM PF00168 | PF06631 | PF09279 | PF00388 | PF00387

Details:
NAME Phospholipase C beta-4-Bos taurus
DESCRIPTION 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4.
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
GENE PLCB4
SEQUENCE 
PVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIED
LFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKQ
GLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVE
MYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPV
ILSFENHCSKYQQYK
 FRAGMENT YES
FUNCTION The production of the second messenger moleculess diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) iss mediated by activated phosphatidylinositol-specific phospholipases C enzymes
Interacting with G-proteins:
Family:Gq/11 REFERENCES:15251227 | 16182515 | 11015615
1GPR0027Galpha-11-Bos taurus
2GPR0039Galpha-14-Bos taurus

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