gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0389 ::
FAMILY Ser Thr protein kinases
SUBFAMILY Kinase suppressor of Ras(KSR)
TYPE Kinase suppressor of Ras(KSR)

Cross References:
UniProt Q8IVT5 | Q13476 EMBL AC069366 | AC015688 | BC042106 | U43586
InterPro IPR002219 | IPR000719 | IPR008271 | IPR001245
PRODOM PD000001 MIM 601132
PFAM PF00130 | PF07714

Details:
NAME Kinase suppressor of Ras(KSR)-Homo sapiens
DESCRIPTION Kinase suppressor of Ras 1.
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE KSR1 | KSR
SEQUENCE 
MDRAALRAAAMGEKKEGGGGGDAAEGGAGAAASRALQQCGQLQKLIDISIGSLRGLRTKC
AVSNDLTQQEIRTLEAKLVRYICKQRQCKLSVAPGERTPELNSYPRFSDWLYTFNVRPEV
VQEIPRDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSS
WSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPS
FSEGLSDTCIPLHAS
 FRAGMENT NO
FUNCTION Location-regulated scaffolding protein connecting MEK tos RAF
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227
1GPR0147Gbeta-1-Homo sapiens
2GPR0155Gbeta-2-Homo sapiens
3GPR0160Gbeta-3-Homo sapiens-1
4GPR0164Gbeta-4-Homo sapiens
5GPR0167Gbeta-5-Homo sapiens-2
6GPR0363Gbeta-3-Homo sapiens-2
7GPR0366Gbeta-5-Homo sapiens-1
8GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227
9GPR0176Ggamma-t1-Homo sapiens
10GPR0179Ggamma-2-Homo sapiens
11GPR0183Ggamma-3-Homo sapiens
12GPR0185Ggamma-4-Homo sapiens
13GPR0188Ggamma-5-Homo sapiens-2
14GPR0192Ggamma-7-Homo sapiens
15GPR0195Ggamma-8-Homo sapiens-2
16GPR0198Ggamma-10-Homo sapiens-2
17GPR0199Ggamma-11-Homo sapiens
18GPR0203Ggamma-12-Homo sapiens
19GPR0205Ggamma-13-Homo sapiens
20GPR0210Ggamma-8-Homo sapiens-1
21GPR0253Ggamma-5-Homo sapiens-1
22GPR0364Ggamma-10-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory