gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0013 ::
FAMILY Cyclases
SUBFAMILY Adenylate cyclases
TYPE Adenylate cyclase 3

Cross References:
UniProt O60266 | Q53T54 | Q9UDB1 EMBL AF033861 | AC012073 | BC126235 | AB011083
InterPro IPR001054
GENEID 109 MIM 600291
PFAM PF00211

Details:
NAME Adenylate cyclase-3-Homo sapiens
DESCRIPTION Adenylate cyclase type 3 (EC 4.6.1.1) (Adenylate cyclase type III)(ATP pyrophosphate-lyase 3) (Adenylyl cyclase 3) (AC-III) (AC3)(Adenylate cyclase, olfactive type).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE ADCY3 | KIAA0511
SEQUENCE 
MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLASLAVAGIGLVLDII
LFVLCKKGLLPDRVTRRVLPYVLWLLITAQIFSYLGLNFARAHAASDTVGWQVFFVFSFF
ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQEELKGMQLLREILANVFLYLCAIAVG
IMSYYMADRKHRKAF
 FRAGMENT NO
FUNCTION Mediates odorant detection (possibly) via modulation ofs intracellular cAMP concentration
Interacting with G-proteins:
Family:Gs REFERENCES:15251227 | 15922020 | 14993377 | 11376933
1GPR0119Galpha-s-Homo sapiens-2
2GPR0263Galpha-s-Homo sapiens-4
3GPR0266Galpha-s-Homo sapiens-5
4GPR0267Galpha-s-Homo sapiens-6
5GPR0277Galpha-s-Homo sapiens-7
6GPR0278Galpha-s-Homo sapiens
7GPR0395Galpha-s-Homo sapiens-3

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