gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0127 ::
FAMILY Tyr protein kinases
SUBFAMILY Tyr protein kinases
TYPE Burtons tyrosine kinase

Cross References:
UniProt P35991 | Q61365 EMBL L08967 | L10627 | L29788 | U58105
InterPro IPR001562 | IPR001849 | IPR011993 | IPR000719 | IPR000980 | IPR001452 | IPR001245 | IPR008266
PRODOM PD000001 | PD000093 | PD000066 GENEID 12229
PRINTS PR00401 | PR00452 | PR00402 | PR00109 PFAM PF00779 | PF00169 | PF07714 | PF00017 | PF00018

Details:
NAME Burton's tyrosine kinase-Mus musculus-2
DESCRIPTION Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase)(Agammaglobulinaemia tyrosine kinase) (ATK) (B-cell progenitor kinase)(BPK) (Kinase EMB).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Btk | Bpk
SEQUENCE 
MAAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEK
ITCVETVIPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEEL
RKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGSLKPGSS
HRKTKKPLPPTPEEDQILKKPLPPEPTAAPISTTELKKVVALYDYMPMNANDLQLRKGEE
YFILEESNLPWWRAR
 FRAGMENT NO
FUNCTION Plays a crucial role in B-cell ontogeny
Interacting with G-proteins:
Family:Gq/11 REFERENCES:15251227 | 9305846 | 16182515
1GPR0240Galpha-q-Mus musculus
Family:Gbeta REFERENCES:15251227 | 11698416
2GPR0148Gbeta-1-Mus musculus
3GPR0156Gbeta-2-Mus musculus
4GPR0161Gbeta-3-Mus musculus
5GPR0165Gbeta-4-Mus musculus
6GPR0168Gbeta-5-Mus musculus-2
7GPR0291unclassified_Gbeta-Mus musculus-1
8GPR0318unclassified_Gbeta-Mus musculus-2
9GPR0376Gbeta-5-Mus musculus-3
10GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:15251227 | 11698416
11GPR0178Ggamma-t1-Mus musculus
12GPR0181Ggamma-2-Mus musculus
13GPR0184Ggamma-3-Mus musculus
14GPR0186Ggamma-4-Mus musculus
15GPR0189Ggamma-5-Mus musculus
16GPR0193Ggamma-7-Mus musculus
17GPR0196Ggamma-8-Mus musculus-2
18GPR0200Ggamma-11-Mus musculus
19GPR0204Ggamma-12-Mus musculus
20GPR0206Ggamma-13-Mus musculus
21GPR0211Ggamma-8-Mus musculus-1
22GPR0349Ggamma-1-Mus musculus
23GPR0379Ggamma-10-Mus musculus

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