gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0245 ::
CLASS Galpha
FAMILY Gi/o
SUBFAMILY Galpha-t
TYPE Galpha-t1

Cross References:
UniProt P04695 EMBL K03253 | K03254 | X02440
InterPro IPR001019 | IPR001408 | IPR011025 PDB 1AQG | 1FQJ | 1FQK | 1GOT | 1LVZ | 1TAD | 1TAG | 1TND
PRODOM PD000281
GENEID 281794
PRINTS PR00318 | PR00441 PFAM PF00503

Details:
NAME Galpha-t1-Bos taurus
DESCRIPTION Guanine nucleotide-binding protein G(t) subunit alpha-1 (Transducinalpha-1 chain).
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
POST TRANSLATION MODIFICATIONS null GENE GNAT1
SEQUENCE
MGAGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLE
ECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPKEMS
DIIQRLWKDSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGI
IETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMH
ESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYNGPNTYEDAGNYIK
VQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0465Phosphodiesterase-6-Bos taurus-1Stimulation15251227 | 15988071 | 14699118
2EFF0466Phosphodiesterase-6-Bos taurus-2Stimulation15251227 | 15988071 | 14699118
3EFF0467Phosphodiesterase-6-Bos taurus-3Stimulation15251227 | 15988071 | 14699118
4EFF0468Phosphodiesterase-6-Bos taurus-4Stimulation15251227 | 15988071 | 14699118

Coupling with GPCRs:
1GPCR1927OPSIN/RHODOPSIN FAMILY_Blue opsin_Bos taurus3867351
2GPCR2086OPSIN/RHODOPSIN FAMILY_Red opsin_Bos taurus3867351
3GPCR2181OPSIN/RHODOPSIN FAMILY_Rhodopsin_Bos taurus3867351




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athina University of Athens
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Biophysics
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