gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0228 ::
CLASS Galpha
FAMILY Gi/o
SUBFAMILY Galpha-i
TYPE Galpha-i2

Cross References:
UniProt O13055 EMBL AB001742
InterPro IPR001019 | IPR001408 | IPR011025
PRODOM PD000281
GENEID 100125814
PRINTS PR00318 | PR00441 PFAM PF00503

Details:
NAME Galpha-i2-Oryzias latipes
DESCRIPTION Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylatecyclase-inhibiting G alpha protein) (Gi2 subunit alpha) (Gi alpha c).
SPECIES Oryzias latipes COMMON NAME Medaka fish NCBI Taxonomy 8090
POST TRANSLATION MODIFICATIONS null GENE gnai2
SEQUENCE
MGCTVSQEDKAAADRSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG
YSEDECKQYRAVVYSNTVQSIMAIIKAMTILHLDYERPEREEDAKRLFKMAAEAEERGDL
PEELANIIKDLWADSGIQHCLTRAREYQLNDSAAYYLKDLERISKPDYIPTQQDVLRTRV
KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVAMSAYDLVLAEDEE
MNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEQKIAHSPLTICFPEYEGPNTYQEA
QAYIQTKFEDLNKKKETKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF1284Tubulin-Oryzias latipesStimulation of GTPase activity10224115 | 15251227 | 16380086

Coupling with GPCRs:
No information




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