gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0208 ::
CLASS Ggamma
FAMILY Ggamma
SUBFAMILY Ggamma
TYPE Ggamma-e

Cross References:
UniProt Q9NFZ3 | A4V0H1 | Q95RZ3 | Q9VLD3 EMBL AJ250440 | AE014134 | AE014134 | AE014134 | AY061031
InterPro IPR015898 | IPR001770
PRODOM PD003783 FlyBase FBgn0028433
GENEID 45234
PRINTS PR00321 PFAM PF00631

Details:
NAME Ggamma-e-Drosophila melanogaster
DESCRIPTION Guanine nucleotide-binding protein subunit gamma-e precursor(Ggamma(e)).
SPECIES Drosophila melanogaster COMMON NAME Fruit fly NCBI Taxonomy 7227
POST TRANSLATION MODIFICATIONS null GENE Ggamma30A | CG3694
SEQUENCE
MDPSALQNMDRDALKKQIENMKYQASMERWPLSKSIAEMRSFIEENEKNDPLINAPDKKN
NPWAEKGKCVIM
FRAGMENT NO
FUNCTION The beta and gamma chains are required for the GTPases activity, for replacement of GDP by GTP, and for G protein-s effector interaction
Effectors:
1EFF0174Calmodulin-Drosophila melanogasterInhibition of calmodulin kinase15251227
2EFF0383Kinase suppressor of Ras(KSR)-Drosophila melanogaster-1Sequestration of Gbeta/gamma15251227
3EFF0384Kinase suppressor of Ras(KSR)-Drosophila melanogaster-2Sequestration of Gbeta/gamma15251227
4EFF0385Kinase suppressor of Ras(KSR)-Drosophila melanogaster-3Sequestration of Gbeta/gamma15251227
5EFF0386Kinase suppressor of Ras(KSR)-Drosophila melanogaster-4Sequestration of Gbeta/gamma15251227
6EFF0387Kinase suppressor of Ras(KSR)-Drosophila melanogaster-5Sequestration of Gbeta/gamma15251227
7EFF0388Kinase suppressor of Ras(KSR)-Drosophila melanogaster-6Sequestration of Gbeta/gamma15251227
8EFF0639Rac-Drosophila melanogaster-2Stimulation,Recruitment to plasma membrane11099498 | 15251227
9EFF0640Rac-Drosophila melanogaster-1Stimulation,Recruitment to plasma membrane11099498 | 15251227
10EFF0729Rho-Drosophila melanogaster-1Recruitment to plasma membrane15251227
11EFF0730Rho-Drosophila melanogaster-2Recruitment to plasma membrane15251227
12EFF0731Rho-Drosophila melanogaster-3Recruitment to plasma membrane15251227
13EFF0732Rho-Drosophila melanogaster-4Recruitment to plasma membrane15251227
14EFF1041Tubulin-Drosophila melanogaster-1Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
15EFF1042Tubulin-Drosophila melanogaster-10Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
16EFF1045Tubulin-Drosophila melanogaster-13Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
17EFF1047Tubulin-Drosophila melanogaster-14Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
18EFF1050Tubulin-Drosophila melanogaster-12Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
19EFF1051Tubulin-Drosophila melanogaster-11Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
20EFF1052Tubulin-Drosophila melanogaster-2Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
21EFF1053Tubulin-Drosophila melanogaster-3Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
22EFF1054Tubulin-Drosophila melanogaster-4Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
23EFF1055Tubulin-Drosophila melanogaster-5Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
24EFF1056Tubulin-Drosophila melanogaster-6Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
25EFF1057Tubulin-Drosophila melanogaster-7Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
26EFF1058Tubulin-Drosophila melanogaster-8Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
27EFF1059Tubulin-Drosophila melanogaster-9Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086

Coupling with GPCRs:
No information




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